Examples of Drugs with Demonstrated Teratogenic Risk in Humans


 Androgens (male hormone) Masculinization of female fetus
 Carbamazepine Craniofacial and fingernail deformities
 Diethylstilbestrol Vaginal tumors and genital malformations in offspring
 Estrogen (female hormone) Feminization of male fetus
 Lithium Cardiac defects
 Phenytoin Craniofacial and limb deformities, growth retardation
 Retinoic acid Craniofacial, cardiac, and *CNS defects
 Thalidomide Phocomelia (limb deformities)
 Warfarin Facial, cartilage, and CNS defects